| 1 | |  Veres Rivne | 30 | 21 | 5 | 4 | 56 | 21 | 35 | 68 | M18:00 | 16/05/21 | R 26  FC Metalist 1925 Kharkiv 4 Veres Rivne 1 B17:00 | 21/05/21 | R 27 Veres Rivne 3 FC Alians Lypova Dolyna 3 M19:00 | 25/05/21 | R 28 Volyn Lutsk 2 Veres Rivne 1 G19:00 | 31/05/21 | R 1 FC Obolon Kiev 0 Veres Rivne 2 G16:00 | 05/06/21 | R 29 Veres Rivne 5 FC Kramatorsk 1 G17:30 | 12/06/21 | R 30 Hirnyk-Sport Horishni Plavni 1 Veres Rivne 2 |
| 2 | |  FC Chornomorets Odessa | 30 | 18 | 7 | 5 | 45 | 23 | 22 | 61 | B16:00 | 07/05/21 | R 25 MFC Mykolaiv 1 FC Chornomorets Odessa 1 M16:00 | 15/05/21 | R 26 Agrobiznes Volochisk 1 FC Chornomorets Odessa 0 G19:00 | 21/05/21 | R 27 FC Chornomorets Odessa 4 Krystal Kherson 0 G19:00 | 27/05/21 | R 28 FC Metalist 1925 Kharkiv 0 FC Chornomorets Odessa 1 M17:30 | 05/06/21 | R 29 FC Chornomorets Odessa 0 FC Alians Lypova Dolyna 2 G17:30 | 12/06/21 | R 30 Volyn Lutsk 1 FC Chornomorets Odessa 2 |
| 3 | |  FC Metalist 1925 Kharkiv | 30 | 16 | 8 | 6 | 36 | 22 | 14 | 56 | B17:00 | 08/05/21 | R 25 FC Obolon Kiev 1 FC Metalist 1925 Kharkiv 1 G18:00 | 16/05/21 | R 26 FC Metalist 1925 Kharkiv 4 Veres Rivne 1 G16:00 | 21/05/21 | R 27 FC Prykarpattya Ivano-Frankivsk 0 FC Metalist 1925 Kharkiv 3 M19:00 | 27/05/21 | R 28 FC Metalist 1925 Kharkiv 0 FC Chornomorets Odessa 1 G17:30 | 05/06/21 | R 29 MFC Kremin Kremenchuk 0 FC Metalist 1925 Kharkiv 4 M17:30 | 12/06/21 | R 30 FC Metalist 1925 Kharkiv 1 Vpk-Agro Shevchenkivka 2 |
| 4 | |  MFC Mykolaiv | 30 | 15 | 8 | 7 | 49 | 23 | 26 | 53 | G17:00 | 15/05/21 | R 26 MFC Mykolaiv 2 MFC Kremin Kremenchuk 0 G17:00 | 21/05/21 | R 27 MFC Mykolaiv 1 Vpk-Agro Shevchenkivka 0 G17:00 | 26/05/21 | R 28 MFC Mykolaiv 4 FC Nyva Ternopil 0 G17:00 | 30/05/21 | R 4 MFC Mykolaiv 2 Volyn Lutsk 1 M17:30 | 05/06/21 | R 29 MFC Mykolaiv 0 FC Polissya Zhytomyr 1 B17:30 | 12/06/21 | R 30 Agrobiznes Volochisk 1 MFC Mykolaiv 1 |
| 5 | |  FC Obolon Kiev | 1 | 1 | 0 | 0 | 4 | 1 | 3 | 3 | |
| 5 | |  Agrobiznes Volochisk | 30 | 15 | 7 | 8 | 46 | 27 | 19 | 52 | M16:00 | 07/05/21 | R 25 FC Prykarpattya Ivano-Frankivsk 2 Agrobiznes Volochisk 1 G16:00 | 15/05/21 | R 26 Agrobiznes Volochisk 1 FC Chornomorets Odessa 0 G17:00 | 21/05/21 | R 27 MFC Kremin Kremenchuk 0 Agrobiznes Volochisk 1 M18:00 | 26/05/21 | R 28 Agrobiznes Volochisk 1 Vpk-Agro Shevchenkivka 2 M17:30 | 05/06/21 | R 29 FC Nyva Ternopil 1 Agrobiznes Volochisk 0 B17:30 | 12/06/21 | R 30 Agrobiznes Volochisk 1 MFC Mykolaiv 1 |
| 6 | |  FC Alians Lypova Dolyna | 30 | 14 | 9 | 7 | 46 | 31 | 15 | 51 | G18:00 | 12/05/21 | R 7 FC Alians Lypova Dolyna 4 FC Polissya Zhytomyr 2 G16:00 | 16/05/21 | R 26 FC Alians Lypova Dolyna 1 FC Obolon Kiev 0 B17:00 | 21/05/21 | R 27 Veres Rivne 3 FC Alians Lypova Dolyna 3 G18:00 | 26/05/21 | R 28 FC Alians Lypova Dolyna 4 FC Prykarpattya Ivano-Frankivsk 1 G17:30 | 05/06/21 | R 29 FC Chornomorets Odessa 0 FC Alians Lypova Dolyna 2 B17:30 | 12/06/21 | R 30 FC Alians Lypova Dolyna 1 MFC Kremin Kremenchuk 1 |
| 7 | |  Volyn Lutsk | 30 | 13 | 7 | 10 | 39 | 28 | 11 | 46 | G15:00 | 16/05/21 | R 26 Volyn Lutsk 2 Hirnyk-Sport Horishni Plavni 0 M18:00 | 21/05/21 | R 27 FC Obolon Kiev 2 Volyn Lutsk 1 G19:00 | 25/05/21 | R 28 Volyn Lutsk 2 Veres Rivne 1 M17:00 | 30/05/21 | R 4 MFC Mykolaiv 2 Volyn Lutsk 1 M17:30 | 05/06/21 | R 29 FC Prykarpattya Ivano-Frankivsk 2 Volyn Lutsk 0 M17:30 | 12/06/21 | R 30 Volyn Lutsk 1 FC Chornomorets Odessa 2 |
| 8 | |  FC Obolon Kiev | 30 | 13 | 4 | 13 | 44 | 35 | 9 | 43 | M16:00 | 16/05/21 | R 26 FC Alians Lypova Dolyna 1 FC Obolon Kiev 0 G18:00 | 21/05/21 | R 27 FC Obolon Kiev 2 Volyn Lutsk 1 G17:00 | 26/05/21 | R 28 FC Kramatorsk 1 FC Obolon Kiev 2 M19:00 | 31/05/21 | R 1 FC Obolon Kiev 0 Veres Rivne 2 M17:30 | 05/06/21 | R 29 FC Obolon Kiev 0 Hirnyk-Sport Horishni Plavni 1 G17:30 | 12/06/21 | R 30 FC Polissya Zhytomyr 1 FC Obolon Kiev 2 |
| 9 | |  Hirnyk-Sport Horishni Plavni | 30 | 11 | 5 | 14 | 43 | 45 | -2 | 38 | M16:00 | 07/05/21 | R 25 Hirnyk-Sport Horishni Plavni 2 FC Alians Lypova Dolyna 3 M15:00 | 16/05/21 | R 26 Volyn Lutsk 2 Hirnyk-Sport Horishni Plavni 0 M17:30 | 21/05/21 | R 27 Hirnyk-Sport Horishni Plavni 0 FC Kramatorsk 2 M18:00 | 26/05/21 | R 28 FC Polissya Zhytomyr 3 Hirnyk-Sport Horishni Plavni 2 G17:30 | 05/06/21 | R 29 FC Obolon Kiev 0 Hirnyk-Sport Horishni Plavni 1 M17:30 | 12/06/21 | R 30 Hirnyk-Sport Horishni Plavni 1 Veres Rivne 2 |
| 10 | |  Vpk-Agro Shevchenkivka | 30 | 11 | 4 | 15 | 30 | 48 | -18 | 37 | M17:00 | 12/05/21 | R 6 Vpk-Agro Shevchenkivka 0 Veres Rivne 4 G16:00 | 16/05/21 | R 26 FC Nyva Ternopil 1 Vpk-Agro Shevchenkivka 2 M17:00 | 21/05/21 | R 27 MFC Mykolaiv 1 Vpk-Agro Shevchenkivka 0 G18:00 | 26/05/21 | R 28 Agrobiznes Volochisk 1 Vpk-Agro Shevchenkivka 2 M17:30 | 05/06/21 | R 29 Vpk-Agro Shevchenkivka 1 Krystal Kherson 2 G17:30 | 12/06/21 | R 30 FC Metalist 1925 Kharkiv 1 Vpk-Agro Shevchenkivka 2 |
| 11 | |  FC Polissya Zhytomyr | 30 | 9 | 8 | 13 | 32 | 37 | -5 | 35 | M18:00 | 12/05/21 | R 7 FC Alians Lypova Dolyna 4 FC Polissya Zhytomyr 2 M17:00 | 16/05/21 | R 26 FC Polissya Zhytomyr 1 FC Kramatorsk 2 M18:00 | 21/05/21 | R 27 FC Nyva Ternopil 2 FC Polissya Zhytomyr 0 G18:00 | 26/05/21 | R 28 FC Polissya Zhytomyr 3 Hirnyk-Sport Horishni Plavni 2 G17:30 | 05/06/21 | R 29 MFC Mykolaiv 0 FC Polissya Zhytomyr 1 M17:30 | 12/06/21 | R 30 FC Polissya Zhytomyr 1 FC Obolon Kiev 2 |
| 12 | |  FC Kramatorsk | 30 | 9 | 5 | 16 | 32 | 51 | -19 | 32 | G17:00 | 16/05/21 | R 26 FC Polissya Zhytomyr 1 FC Kramatorsk 2 G17:30 | 21/05/21 | R 27 Hirnyk-Sport Horishni Plavni 0 FC Kramatorsk 2 M17:00 | 26/05/21 | R 28 FC Kramatorsk 1 FC Obolon Kiev 2 M16:00 | 30/05/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Kramatorsk 1 M16:00 | 05/06/21 | R 29 Veres Rivne 5 FC Kramatorsk 1 G17:30 | 12/06/21 | R 30 FC Kramatorsk 3 FC Prykarpattya Ivano-Frankivsk 1 |
| 13 | |  FC Nyva Ternopil | 30 | 8 | 7 | 15 | 30 | 50 | -20 | 31 | G15:30 | 07/05/21 | R 25 MFC Kremin Kremenchuk 1 FC Nyva Ternopil 3 M16:00 | 16/05/21 | R 26 FC Nyva Ternopil 1 Vpk-Agro Shevchenkivka 2 G18:00 | 21/05/21 | R 27 FC Nyva Ternopil 2 FC Polissya Zhytomyr 0 M17:00 | 26/05/21 | R 28 MFC Mykolaiv 4 FC Nyva Ternopil 0 G17:30 | 05/06/21 | R 29 FC Nyva Ternopil 1 Agrobiznes Volochisk 0 B17:30 | 12/06/21 | R 30 Krystal Kherson 1 FC Nyva Ternopil 1 |
| 14 | |  FC Prykarpattya Ivano-Frankivsk | 30 | 8 | 6 | 16 | 25 | 45 | -20 | 30 | G15:00 | 16/05/21 | R 26 Krystal Kherson 0 FC Prykarpattya Ivano-Frankivsk 1 M16:00 | 21/05/21 | R 27 FC Prykarpattya Ivano-Frankivsk 0 FC Metalist 1925 Kharkiv 3 M18:00 | 26/05/21 | R 28 FC Alians Lypova Dolyna 4 FC Prykarpattya Ivano-Frankivsk 1 G16:00 | 30/05/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Kramatorsk 1 G17:30 | 05/06/21 | R 29 FC Prykarpattya Ivano-Frankivsk 2 Volyn Lutsk 0 M17:30 | 12/06/21 | R 30 FC Kramatorsk 3 FC Prykarpattya Ivano-Frankivsk 1 |
| 15 | |  MFC Kremin Kremenchuk | 30 | 6 | 6 | 18 | 23 | 50 | -27 | 24 | M15:30 | 07/05/21 | R 25 MFC Kremin Kremenchuk 1 FC Nyva Ternopil 3 M17:00 | 15/05/21 | R 26 MFC Mykolaiv 2 MFC Kremin Kremenchuk 0 M17:00 | 21/05/21 | R 27 MFC Kremin Kremenchuk 0 Agrobiznes Volochisk 1 G17:00 | 26/05/21 | R 28 Krystal Kherson 1 MFC Kremin Kremenchuk 2 M17:30 | 05/06/21 | R 29 MFC Kremin Kremenchuk 0 FC Metalist 1925 Kharkiv 4 B17:30 | 12/06/21 | R 30 FC Alians Lypova Dolyna 1 MFC Kremin Kremenchuk 1 |
| 16 | |  Krystal Kherson | 30 | 3 | 4 | 23 | 21 | 61 | -40 | 13 | M16:00 | 07/05/21 | R 25 Veres Rivne 2 Krystal Kherson 0 M15:00 | 16/05/21 | R 26 Krystal Kherson 0 FC Prykarpattya Ivano-Frankivsk 1 M19:00 | 21/05/21 | R 27 FC Chornomorets Odessa 4 Krystal Kherson 0 M17:00 | 26/05/21 | R 28 Krystal Kherson 1 MFC Kremin Kremenchuk 2 G17:30 | 05/06/21 | R 29 Vpk-Agro Shevchenkivka 1 Krystal Kherson 2 B17:30 | 12/06/21 | R 30 Krystal Kherson 1 FC Nyva Ternopil 1 |
