| 1 | |  Manchester United FC | 38 | 28 | 7 | 3 | 97 | 45 | 52 | 91 | G19:00 | 15/04/00  Manchester United FC 4 Sunderland 0 G19:00 | 22/04/00 Southampton 1 Manchester United FC 3 G19:00 | 24/04/00 Manchester United FC 3 Chelsea 2 G19:00 | 29/04/00 Watford 2 Manchester United FC 3 G19:00 | 06/05/00 Manchester United FC 3 Tottenham 1 G19:00 | 14/05/00 Aston Villa 0 Manchester United FC 1 |
| 2 | |  Arsenal FC | 38 | 22 | 7 | 9 | 73 | 43 | 30 | 73 | G19:00 | 23/04/00 Watford 2 Arsenal FC 3 G19:00 | 29/04/00 Everton FC 0 Arsenal FC 1 G19:00 | 02/05/00 Arsenal FC 2 West Ham United FC 1 G19:00 | 06/05/00 Arsenal FC 2 Chelsea 1 B19:00 | 09/05/00 Arsenal FC 3 Sheffield Wednesday 3 M19:00 | 14/05/00 Newcastle United FC 4 Arsenal FC 2 |
| 3 | |  Leeds United | 38 | 21 | 6 | 11 | 58 | 43 | 15 | 69 | M19:00 | 16/04/00 Leeds United 0 Arsenal FC 4 B19:00 | 23/04/00 Newcastle United FC 2 Leeds United 2 G19:00 | 30/04/00 Sheffield Wednesday 0 Leeds United 3 G19:00 | 03/05/00 Leeds United 3 Watford 1 B19:00 | 08/05/00 Leeds United 1 Everton FC 1 B19:00 | 14/05/00 West Ham United FC 0 Leeds United 0 |
| 4 | |  Liverpool | 38 | 19 | 10 | 9 | 51 | 30 | 21 | 67 | G19:00 | 16/04/00 Milton Keynes Dons 1 Liverpool 2 B19:00 | 21/04/00 Everton FC 0 Liverpool 0 M19:00 | 03/05/00 Liverpool 0 Leicester City FC 2 B19:00 | 07/05/00 Liverpool 0 Southampton 0 M19:00 | 14/05/00 Bradford City 1 Liverpool 0 |
| 5 | |  Chelsea | 38 | 18 | 11 | 9 | 53 | 34 | 19 | 65 | M19:00 | 15/04/00 Sheffield Wednesday 1 Chelsea 0 B19:00 | 22/04/00 Chelsea 1 Middlesbrough 1 M19:00 | 24/04/00 Manchester United FC 3 Chelsea 2 M19:00 | 06/05/00 Arsenal FC 2 Chelsea 1 G19:00 | 14/05/00 Chelsea 4 Derby County 0 |
| 6 | |  Aston Villa | 38 | 15 | 13 | 10 | 46 | 35 | 11 | 58 | G19:00 | 09/04/00 Aston Villa 1 Leeds United 0 G19:00 | 15/04/00 Tottenham 2 Aston Villa 4 B19:00 | 22/04/00 Aston Villa 2 Leicester City FC 2 B19:00 | 29/04/00 Aston Villa 1 Sunderland 1 B19:00 | 06/05/00 Milton Keynes Dons 2 Aston Villa 2 M19:00 | 14/05/00 Aston Villa 0 Manchester United FC 1 |
| 7 | |  Sunderland | 38 | 16 | 10 | 12 | 57 | 56 | 1 | 58 | M19:00 | 15/04/00 Manchester United FC 4 Sunderland 0 G19:00 | 22/04/00 Sheffield Wednesday 0 Sunderland 2 M19:00 | 24/04/00 Sunderland 0 Bradford City 1 B19:00 | 29/04/00 Aston Villa 1 Sunderland 1 G19:00 | 06/05/00 Sunderland 1 West Ham United FC 0 M19:00 | 14/05/00 Tottenham 3 Sunderland 1 |
| 8 | |  Leicester City FC | 38 | 16 | 7 | 15 | 55 | 55 | 0 | 55 | M19:00 | 19/04/00 Leicester City FC 0 Tottenham 1 B19:00 | 22/04/00 Aston Villa 2 Leicester City FC 2 G19:00 | 29/04/00 Southampton 1 Leicester City FC 2 G19:00 | 03/05/00 Liverpool 0 Leicester City FC 2 G19:00 | 06/05/00 Leicester City FC 3 Bradford City 0 M19:00 | 14/05/00 Sheffield Wednesday 4 Leicester City FC 0 |
| 9 | |  West Ham United FC | 38 | 15 | 10 | 13 | 52 | 53 | -1 | 55 | G19:00 | 15/04/00 Derby County 1 West Ham United FC 2 G19:00 | 22/04/00 West Ham United FC 5 Coventry City 0 M19:00 | 29/04/00 West Ham United FC 0 Middlesbrough 1 M19:00 | 02/05/00 Arsenal FC 2 West Ham United FC 1 M19:00 | 06/05/00 Sunderland 1 West Ham United FC 0 B19:00 | 14/05/00 West Ham United FC 0 Leeds United 0 |
| 10 | |  Tottenham | 38 | 15 | 8 | 15 | 57 | 49 | 8 | 53 | M19:00 | 15/04/00 Tottenham 2 Aston Villa 4 G19:00 | 19/04/00 Leicester City FC 0 Tottenham 1 G19:00 | 22/04/00 Tottenham 2 Milton Keynes Dons 0 B19:00 | 29/04/00 Tottenham 1 Derby County 1 M19:00 | 06/05/00 Manchester United FC 3 Tottenham 1 G19:00 | 14/05/00 Tottenham 3 Sunderland 1 |
| 11 | |  Newcastle United FC | 38 | 14 | 10 | 14 | 63 | 54 | 9 | 52 | M19:00 | 15/04/00 Newcastle United FC 0 Leicester City FC 2 B19:00 | 23/04/00 Newcastle United FC 2 Leeds United 2 G19:00 | 29/04/00 Newcastle United FC 2 Coventry City 0 B19:00 | 02/05/00 Middlesbrough 2 Newcastle United FC 2 B19:00 | 06/05/00 Derby County 0 Newcastle United FC 0 G19:00 | 14/05/00 Newcastle United FC 4 Arsenal FC 2 |
| 12 | |  Middlesbrough | 38 | 14 | 10 | 14 | 46 | 52 | -6 | 52 | M19:00 | 15/04/00 Coventry City 2 Middlesbrough 1 B19:00 | 22/04/00 Chelsea 1 Middlesbrough 1 G19:00 | 29/04/00 West Ham United FC 0 Middlesbrough 1 B19:00 | 02/05/00 Middlesbrough 2 Newcastle United FC 2 B19:00 | 06/05/00 Middlesbrough 1 Watford 1 G19:00 | 14/05/00 Everton FC 0 Middlesbrough 2 |
| 13 | |  Everton FC | 38 | 12 | 14 | 12 | 59 | 49 | 10 | 50 | B19:00 | 08/04/00 Leicester City FC 1 Everton FC 1 G19:00 | 15/04/00 Everton FC 4 Bradford City 0 B19:00 | 21/04/00 Everton FC 0 Liverpool 0 M19:00 | 29/04/00 Everton FC 0 Arsenal FC 1 B19:00 | 08/05/00 Leeds United 1 Everton FC 1 M19:00 | 14/05/00 Everton FC 0 Middlesbrough 2 |
| 14 | |  Coventry City | 38 | 12 | 8 | 18 | 47 | 54 | -7 | 44 | M19:00 | 12/04/00 Chelsea 2 Coventry City 1 G19:00 | 15/04/00 Coventry City 2 Middlesbrough 1 M19:00 | 22/04/00 West Ham United FC 5 Coventry City 0 M19:00 | 29/04/00 Newcastle United FC 2 Coventry City 0 G19:00 | 06/05/00 Coventry City 4 Sheffield Wednesday 1 M19:00 | 14/05/00 Watford 1 Coventry City 0 |
| 15 | |  Southampton | 38 | 12 | 8 | 18 | 45 | 62 | -17 | 44 | G19:00 | 15/04/00 Southampton 2 Watford 0 M19:00 | 22/04/00 Southampton 1 Manchester United FC 3 M19:00 | 24/04/00 Derby County 2 Southampton 0 M19:00 | 29/04/00 Southampton 1 Leicester City FC 2 B19:00 | 07/05/00 Liverpool 0 Southampton 0 G19:00 | 14/05/00 Southampton 2 Milton Keynes Dons 0 |
| 16 | |  Derby County | 38 | 9 | 11 | 18 | 44 | 57 | -13 | 38 | M19:00 | 15/04/00 Derby County 1 West Ham United FC 2 B19:00 | 21/04/00 Bradford City 4 Derby County 4 G19:00 | 24/04/00 Derby County 2 Southampton 0 B19:00 | 29/04/00 Tottenham 1 Derby County 1 B19:00 | 06/05/00 Derby County 0 Newcastle United FC 0 M19:00 | 14/05/00 Chelsea 4 Derby County 0 |
| 17 | |  Bradford City | 38 | 9 | 9 | 20 | 38 | 68 | -30 | 36 | M19:00 | 15/04/00 Everton FC 4 Bradford City 0 B19:00 | 21/04/00 Bradford City 4 Derby County 4 G19:00 | 24/04/00 Sunderland 0 Bradford City 1 G19:00 | 30/04/00 Bradford City 3 Milton Keynes Dons 0 M19:00 | 06/05/00 Leicester City FC 3 Bradford City 0 G19:00 | 14/05/00 Bradford City 1 Liverpool 0 |
| 18 | |  Milton Keynes Dons | 38 | 7 | 12 | 19 | 46 | 74 | -28 | 33 | M19:00 | 12/04/00 Milton Keynes Dons 0 Sheffield Wednesday 2 M19:00 | 16/04/00 Milton Keynes Dons 1 Liverpool 2 M19:00 | 22/04/00 Tottenham 2 Milton Keynes Dons 0 M19:00 | 30/04/00 Bradford City 3 Milton Keynes Dons 0 B19:00 | 06/05/00 Milton Keynes Dons 2 Aston Villa 2 M19:00 | 14/05/00 Southampton 2 Milton Keynes Dons 0 |
| 19 | |  Sheffield Wednesday | 38 | 8 | 7 | 23 | 38 | 70 | -32 | 31 | G19:00 | 15/04/00 Sheffield Wednesday 1 Chelsea 0 M19:00 | 22/04/00 Sheffield Wednesday 0 Sunderland 2 M19:00 | 30/04/00 Sheffield Wednesday 0 Leeds United 3 M19:00 | 06/05/00 Coventry City 4 Sheffield Wednesday 1 B19:00 | 09/05/00 Arsenal FC 3 Sheffield Wednesday 3 G19:00 | 14/05/00 Sheffield Wednesday 4 Leicester City FC 0 |
| 20 | |  Watford | 38 | 6 | 6 | 26 | 35 | 77 | -42 | 24 | M19:00 | 15/04/00 Southampton 2 Watford 0 M19:00 | 23/04/00 Watford 2 Arsenal FC 3 M19:00 | 29/04/00 Watford 2 Manchester United FC 3 M19:00 | 03/05/00 Leeds United 3 Watford 1 B19:00 | 06/05/00 Middlesbrough 1 Watford 1 G19:00 | 14/05/00 Watford 1 Coventry City 0 |
